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Proteins containing expanded polyglutamine tracts and neurodegenerative disease

Several hereditary neurological and neuromuscular diseases are caused by an abnormal expansion of trinucleotide repeats. To date, there have been ten of these trinucleotide repeat disorders associated with an expansion of the codon CAG encoding glutamine (Q). For these polyglutamine (polyQ) diseases...

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Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Adegbuyiro, Adewale, Sedighi, Faezeh, Pilkington, Albert W., Groover, Sharon, Legleiter, Justin
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727916/
https://ncbi.nlm.nih.gov/pubmed/28170216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00936
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