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Intracellular degradation of misfolded proteins in polyglutamine neurodegenerative diseases
A number of neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and polyglutamine diseases, are characterized by the age-dependent formation of intracellular protein aggregates and neurodegeneration. Although there is some debate surrounding the role of these aggregates in neurotoxicity,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577582/ https://ncbi.nlm.nih.gov/pubmed/18773920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresrev.2008.08.003 |
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