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Polyglutamine Repeats in Neurodegenerative Diseases
Among the age-dependent protein aggregation disorders, nine neurodegenerative diseases are caused by expansions of CAG repeats encoding polyglutamine (polyQ) tracts. We review the clinical, pathological, and biological features of these inherited disorders. We discuss insights into pathogenesis glea...
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| Publicado no: | Annu Rev Pathol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6387631/ https://ncbi.nlm.nih.gov/pubmed/30089230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathmechdis-012418-012857 |
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