Physiologic changes associated with cerebellar dystonia

Por Shakkottai, Vikram G.
Publicado em 2014

Translating cerebellar Purkinje neuron physiology to progress in dominantly inherited ataxia

Por Chopra, Ravi, Shakkottai, Vikram G
Publicado em 2014

The Role for Alterations in Neuronal Activity in the Pathogenesis of Polyglutamine Repeat Disorders

Por Chopra, Ravi, Shakkottai, Vikram G.
Publicado no Neurotherapeutics (2014)

Physiologic alterations in ataxia: Channeling changes into novel therapies

Por Shakkottai, Vikram G., Paulson, Henry L.
Publicado em 2009

Autosomal Dominant Spinocerebellar Ataxia

Por Shakkottai, Vikram G., Fogel, Brent L.
Publicado em 2013

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease

Por Bushart, David D., Murphy, Geoffrey G., Shakkottai, Vikram G.
Publicado no Ann Transl Med (2016)

Temporal and cell-specific deletion establishes that neuronal Npc1 deficiency is sufficient to mediate neurodegeneration

Por Yu, Ting, Shakkottai, Vikram G., Chung, Chan, Lieberman, Andrew P.
Publicado em 2011

FGF14 Regulates the Intrinsic Excitability of Cerebellar Purkinje Neurons

Por Shakkottai, Vikram G., Xiao, Maolei, Xu, Lin, Wong, Michael, Nerbonne, Jeanne M., Ornitz, David M., Yamada, Kelvin A.
Publicado em 2008

Early Changes in Cerebellar Physiology Accompany Motor Dysfunction in the Polyglutamine Disease Spinocerebellar Ataxia Type 3

Por Shakkottai, Vikram G., do Carmo Costa, Maria, Dell'Orco, James M., Sankaranarayanan, Ananthakrishnan, Wulff, Heike, Paulson, Henry L.
Publicado em 2011

Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcay(ji-hes) mice

Por Luna-Cancalon, Katiuska, Sikora, Kristine M., Pappas, Samuel S., Singh, Vikrant, Wulff, Heike, Paulson, Henry L., Burmeister, Margit, Shakkottai, Vikram G.
Publicado em 2014

Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration

Por Elrick, Matthew J., Pacheco, Chris D., Yu, Ting, Dadgar, Nahid, Shakkottai, Vikram G., Ware, Christopher, Paulson, Henry L., Lieberman, Andrew P.
Publicado em 2010

Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease

Por Chung, Chan, Elrick, Matthew J., Dell’Orco, James M., Qin, Zhaohui S., Kalyana-Sundaram, Shanker, Chinnaiyan, Arul M., Shakkottai, Vikram G., Lieberman, Andrew P.
Publicado no PLoS Genet (2016)

Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia

Por Shakkottai, Vikram G., Chou, Chin-hua, Oddo, Salvatore, Sailer, Claudia A., Knaus, Hans-Günther, Gutman, George A., Barish, Michael E., LaFerla, Frank M., Chandy, K. George
Publicado em 2004

Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability

Por Dell'Orco, James M., Wasserman, Aaron H., Chopra, Ravi, Ingram, Melissa A. C., Hu, Yuan-Shih, Singh, Vikrant, Wulff, Heike, Opal, Puneet, Orr, Harry T., Shakkottai, Vikram G.
Publicado no J Neurosci (2015)

Toward RNAi Therapy for the Polyglutamine Disease Machado–Joseph Disease

Por do Carmo Costa, Maria, Luna-Cancalon, Katiuska, Fischer, Svetlana, Ashraf, Naila S, Ouyang, Michelle, Dharia, Rahil M, Martin-Fishman, Lucas, Yang, Yemen, Shakkottai, Vikram G, Davidson, Beverly L, Rodríguez-Lebrón, Edgardo, Paulson, Henry L
Publicado em 2013

Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Na(v)1.6) in a mouse mutant with a chronic movement disorder

Por Jones, Julie M., Dionne, Louise, Dell’Orco, James, Parent, Rachel, Krueger, Jamie N., Cheng, Xiaoyang, Dib-Hajj, Sulayman D., Bunton-Stasyshyn, Rosie K., Sharkey, Lisa M., Dowling, James J., Murphy, Geoffrey G., Shakkottai, Vikram G., Shrager, Peter, Meisler, Miriam H.
Publicado no Neurobiol Dis (2016)

Coenzyme Q10 and Spinocerebellar Ataxias

Por Lo, Raymond Y., Figueroa, Karla P., Pulst, Stefan M., Lin, Chi-Ying, Perlman, Susan, Wilmot, George, Gomez, Christopher, Schmahmann, Jeremy, Paulson, Henry, Shakkottai, Vikram G., Ying, Sarah, Zesiewicz, Theresa, Bushara, Khalaf, Geschwind, Michael, Xia, Guangbin, Subramony, S.H., Ashizawa, Tetsuo, Kuo, Sheng-Han
Publicado no Mov Disord (2014)

Vascular Risk Factors and Clinical Progression in Spinocerebellar Ataxias

Por Lo, Raymond Y., Figueroa, Karla P., Pulst, Stefan M., Lin, Chi-Ying, Perlman, Susan, Wilmot, George, Gomez, Christopher M., Schmahmann, Jeremy, Paulson, Henry, Shakkottai, Vikram G., Ying, Sarah H., Zesiewicz, Theresa, Bushara, Khalaf, Geschwind, Michael, Xia, Guangbin, Subramony, S. H., Ashizawa, Tetsuo, Kuo, Sheng-Han
Publicado no Tremor Other Hyperkinet Mov (N Y) (2015)

Depression and Clinical Progression in Spinocerebellar Ataxias

Por Lo, Raymond Y., Figueroa, Karla P, Pulst, Stefan M, Perlman, Susan, Wilmot, George, Gomez, Christopher, Schmahmann, Jeremy, Paulson, Henry, Shakkottai, Vikram G., Ying, Sarah, Zesiewicz, Theresa, Bushara, Khalaf, Geschwind, Michael, Xia, Guangbin, Yu, Jui-Tsen, Lee, Lue-En, Ashizawa, Tetsuo, Subramony, SH, Kuo, Sheng-Han
Publicado no Parkinsonism Relat Disord (2015)

Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia

Por Shakkottai, Vikram G., Batla, Amit, Bhatia, Kailash, Dauer, William T, Dresel, Christian, Niethammer, Martin, Eidelberg, David, Raike, Robert S., Smith, Yoland, Jinnah, H. A., Hess, Ellen J., Meunier, Sabine, Hallett, Mark, Fremont, Rachel, Khodakhah, Kamran, LeDoux, Mark S., Popa, Traian, Gallea, Cécile, Lehericy, Stéphane, Bostan, Andreea C., Strick, Peter L.
Publicado no Cerebellum (2017)