Physiologic changes associated with cerebellar dystonia

por Shakkottai, Vikram G.
Publicado 2014

Translating cerebellar Purkinje neuron physiology to progress in dominantly inherited ataxia

por Chopra, Ravi, Shakkottai, Vikram G
Publicado 2014

The Role for Alterations in Neuronal Activity in the Pathogenesis of Polyglutamine Repeat Disorders

por Chopra, Ravi, Shakkottai, Vikram G.
Publicado en Neurotherapeutics (2014)

Physiologic alterations in ataxia: Channeling changes into novel therapies

por Shakkottai, Vikram G., Paulson, Henry L.
Publicado 2009

Autosomal Dominant Spinocerebellar Ataxia

por Shakkottai, Vikram G., Fogel, Brent L.
Publicado 2013

Ion channel dysfunction in cerebellar ataxia

por Bushart, David D, Shakkottai, Vikram G
Publicado en Neurosci Lett (2018)

Moving Towards Therapy in SCA1: Insights from Molecular Mechanisms, Identification of Novel Targets, and Planning for Human Trials

por Srinivasan, Sharan R., Shakkottai, Vikram G.
Publicado en Neurotherapeutics (2019)

Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1

por Chopra, Ravi, Bushart, David D., Shakkottai, Vikram G.
Publicado en PLoS One (2018)

Alanyl-tRNA Synthetase 2 (AARS2)-Related Ataxia without Leukoencephalopathy

por Kuo, Molly E., Antonellis, Anthony, Shakkottai, Vikram G.
Publicado en Cerebellum (2020)

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease

por Bushart, David D., Murphy, Geoffrey G., Shakkottai, Vikram G.
Publicado en Ann Transl Med (2016)

Polyglutamine Repeats in Neurodegenerative Diseases

por Lieberman, Andrew P., Shakkottai, Vikram G., Albin, Roger L.
Publicado en Annu Rev Pathol (2018)

Temporal and cell-specific deletion establishes that neuronal Npc1 deficiency is sufficient to mediate neurodegeneration

por Yu, Ting, Shakkottai, Vikram G., Chung, Chan, Lieberman, Andrew P.
Publicado 2011

Potassium channel dysfunction underlies Purkinje neuron spiking abnormalities in spinocerebellar ataxia type 2

por Dell’Orco, James M, Pulst, Stefan M, Shakkottai, Vikram G
Publicado en Hum Mol Genet (2017)

Polyglutamine spinocerebellar ataxias — from genes to potential treatments

por Paulson, Henry L., Shakkottai, Vikram G., Brent Clark, H., Orr, Harry T.
Publicado en Nat Rev Neurosci (2017)

SK(Ca) Channels Mediate the Medium But Not the Slow Calcium-Activated Afterhyperpolarization in Cortical Neurons

por Villalobos, Claudio, Shakkottai, Vikram G., Chandy, K. George, Michelhaugh, Sharon K., Andrade, Rodrigo
Publicado en J Neurosci (2004)

A chlorzoxazone-baclofen combination improves cerebellar impairment in spinocerebellar ataxia type 1

por Bushart, David D., Huang, Haoran, Man, Luke J., Morrison, Logan M., Shakkottai, Vikram G.
Publicado en Mov Disord (2020)

Targeting potassium channels to treat cerebellar ataxia

por Bushart, David D., Chopra, Ravi, Singh, Vikrant, Murphy, Geoffrey G., Wulff, Heike, Shakkottai, Vikram G.
Publicado en Ann Clin Transl Neurol (2018)

Protein kinase C activity is a protective modifier of Purkinje neuron degeneration in cerebellar ataxia

por Chopra, Ravi, Wasserman, Aaron H, Pulst, Stefan M, De Zeeuw, Chris I, Shakkottai, Vikram G
Publicado en Hum Mol Genet (2018)

Multiple system atrophy pathology is associated with primary Sjögren’s syndrome

por Conway, Kyle S., Camelo-Piragua, Sandra, Fisher-Hubbard, Amanda, Perry, William R., Shakkottai, Vikram G., Venneti, Sriram
Publicado en JCI Insight (2020)

FGF14 Regulates the Intrinsic Excitability of Cerebellar Purkinje Neurons

por Shakkottai, Vikram G., Xiao, Maolei, Xu, Lin, Wong, Michael, Nerbonne, Jeanne M., Ornitz, David M., Yamada, Kelvin A.
Publicado 2008