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Polyglutamine spinocerebellar ataxias — from genes to potential treatments
The dominantly inherited spinocerebellar ataxias (SCAs) are a large and diverse group of neurodegenerative diseases. The most prevalent SCAs (SCA1, SCA2, SCA3, SCA6 and SCA7) are caused by expansion of a glutamine-encoding CAG repeat in the affected gene. These SCAs represent a substantial portion o...
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| Published in: | Nat Rev Neurosci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420820/ https://ncbi.nlm.nih.gov/pubmed/28855740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn.2017.92 |
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