Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution

Archaeal DNA polymerases from the B-family (polB) have found essential applications in biotechnology. In addition, some of their variants can accept a wide range of modified nucleotides or xenobiotic nucleotides, such as 1,5-anhydrohexitol nucleic acid (HNA), which has the unique ability to selectiv...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Biomolecules
Main Authors: Samson, Camille, Legrand, Pierre, Tekpinar, Mustafa, Rozenski, Jef, Abramov, Mikhail, Holliger, Philipp, Pinheiro, Vitor B., Herdewijn, Piet, Delarue, Marc
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763228/
https://ncbi.nlm.nih.gov/pubmed/33302546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10121647
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker