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Evolving a polymerase for hydrophobic base analogues
Hydrophobic base analogues (HBAs) have shown great promise for the expansion of the chemical and coding potential of nucleic acids but are generally poor polymerase substrates. While extensive synthetic efforts have yielded examples of HBAs with favourable substrate properties, their discovery has r...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762193/ https://ncbi.nlm.nih.gov/pubmed/19778048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9039696 |
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