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Hydrophobic, Non-Hydrogen-Bonding Bases and Base Pairs in DNA

We report the properties of hydrophobic isosteres of pyrimidines and purines in synthetic DNA duplexes. Phenyl nucleosides 1 and 2 are nonpolar isosteres of the natural thymidine nucleoside, and indole nucleoside 3 is an analog of the complementary purine 2-aminodeoxyadenosine. The nucleosides were...

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Bibliografske podrobnosti
Main Authors: Schweitzer, Barbara A., Kool, Eric T.
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946113/
https://ncbi.nlm.nih.gov/pubmed/20882111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja00112a001
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