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Hydrophobic, Non-Hydrogen-Bonding Bases and Base Pairs in DNA
We report the properties of hydrophobic isosteres of pyrimidines and purines in synthetic DNA duplexes. Phenyl nucleosides 1 and 2 are nonpolar isosteres of the natural thymidine nucleoside, and indole nucleoside 3 is an analog of the complementary purine 2-aminodeoxyadenosine. The nucleosides were...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946113/ https://ncbi.nlm.nih.gov/pubmed/20882111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja00112a001 |
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