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Measurement and Theory of Hydrogen Bonding Contribution to Isosteric DNA Base Pairs
We address the recent debate surrounding the ability of 2,4-difluorotoluene (F), a low-polarity mimic of thymine (T), to form a hydrogen-bonded complex with adenine in DNA. The hydrogen bonding ability of F has been characterized as small to zero in various experimental studies, and moderate to smal...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293652/ https://ncbi.nlm.nih.gov/pubmed/22300089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210475a |
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