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Hydrophobic, Non-Hydrogen-Bonding Bases and Base Pairs in DNA

We report the properties of hydrophobic isosteres of pyrimidines and purines in synthetic DNA duplexes. Phenyl nucleosides 1 and 2 are nonpolar isosteres of the natural thymidine nucleoside, and indole nucleoside 3 is an analog of the complementary purine 2-aminodeoxyadenosine. The nucleosides were...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schweitzer, Barbara A., Kool, Eric T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946113/
https://ncbi.nlm.nih.gov/pubmed/20882111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja00112a001
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