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Recognition of threosyl nucleotides by DNA and RNA polymerases

α-l-Threose nucleic acids (TNA) are potentially natural nucleic acids that could have acted as an evolutionary alternative to RNA. We determined whether DNA or RNA polymerases could recognize phosphorylated threosyl nucleosides. We found that for both the Vent (exo(–)) DNA polymerase and HIV reverse...

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Bibliografische gegevens
Hoofdauteurs: Kempeneers, Veerle, Vastmans, Karen, Rozenski, Jef, Herdewijn, Piet
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC275475/
https://ncbi.nlm.nih.gov/pubmed/14576309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg833
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