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Recognition of threosyl nucleotides by DNA and RNA polymerases

α-l-Threose nucleic acids (TNA) are potentially natural nucleic acids that could have acted as an evolutionary alternative to RNA. We determined whether DNA or RNA polymerases could recognize phosphorylated threosyl nucleosides. We found that for both the Vent (exo(–)) DNA polymerase and HIV reverse...

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Detalhes bibliográficos
Main Authors: Kempeneers, Veerle, Vastmans, Karen, Rozenski, Jef, Herdewijn, Piet
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC275475/
https://ncbi.nlm.nih.gov/pubmed/14576309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg833
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