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Recognition of threosyl nucleotides by DNA and RNA polymerases

α-l-Threose nucleic acids (TNA) are potentially natural nucleic acids that could have acted as an evolutionary alternative to RNA. We determined whether DNA or RNA polymerases could recognize phosphorylated threosyl nucleosides. We found that for both the Vent (exo(–)) DNA polymerase and HIV reverse...

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Autori principali: Kempeneers, Veerle, Vastmans, Karen, Rozenski, Jef, Herdewijn, Piet
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC275475/
https://ncbi.nlm.nih.gov/pubmed/14576309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg833
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