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Degradation of Intrinsically Disordered Proteins by the NADH 26S Proteasome

The 26S proteasome is the endpoint of the ubiquitin- and ATP-dependent degradation pathway. Over the years, ATP was regarded as completely essential for 26S proteasome function due to its role in ubiquitin-signaling, substrate unfolding and ensuring its structural integrity. We have previously repor...

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Vydáno v:Biomolecules
Hlavní autoři: Tsvetkov, Peter, Myers, Nadav, Adler, Julia, Shaul, Yosef
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762313/
https://ncbi.nlm.nih.gov/pubmed/33297334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10121642
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