A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

Por Asher, Gad, Tsvetkov, Peter, Kahana, Chaim, Shaul, Yosef
Publicado em 2005

Susceptibility of p53 Unstructured N Terminus to 20 S Proteasomal Degradation Programs the Stress Response

Por Tsvetkov, Peter, Reuven, Nina, Prives, Carol, Shaul, Yosef
Publicado em 2009

E3 Ligase STUB1/CHIP Regulates NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Accumulation in Aged Brain, a Process Impaired in Certain Alzheimer Disease Patients

Por Tsvetkov, Peter, Adamovich, Yaarit, Elliott, Evan, Shaul, Yosef
Publicado em 2011

p53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1

Por Asher, Gad, Lotem, Joseph, Tsvetkov, Peter, Reiss, Veronica, Sachs, Leo, Shaul, Yosef
Publicado em 2003

Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin

Por Tsvetkov, Peter, Asher, Gad, Reiss, Veronica, Shaul, Yosef, Sachs, Leo, Lotem, Joseph
Publicado em 2005

NADH Binds and Stabilizes the 26S Proteasomes Independent of ATP

Por Tsvetkov, Peter, Myers, Nadav, Eliav, Raz, Adamovich, Yaarit, Hagai, Tzachi, Adler, Julia, Navon, Ami, Shaul, Yosef
Publicado em 2014

The Protein Level of PGC-1α, a Key Metabolic Regulator, Is Controlled by NADH-NQO1

Por Adamovich, Yaarit, Shlomai, Amir, Tsvetkov, Peter, Umansky, Kfir B., Reuven, Nina, Estall, Jennifer L., Spiegelman, Bruce M., Shaul, Yosef
Publicado em 2013

Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers

Por Tsvetkov, Peter, Sokol, Ethan, Jin, Dexter, Brune, Zarina, Thiru, Prathapan, Ghandi, Mahmoud, Garraway, Levi A., Gupta, Piyush B., Santagata, Sandro, Whitesell, Luke, Lindquist, Susan
Publicado no Proc Natl Acad Sci U S A (2017)

A genetic tool to track protein aggregates and control prion inheritance

Por Newby, Gregory A., Kiriakov, Szilvia, Hallacli, Erinc, Kayatekin, Can, Tsvetkov, Peter, Mancuso, Christopher P., Bonner, J. Maeve, Hesse, William R., Chakrabortee, Sohini, Manogaran, Anita L., Liebman, Susan W., Lindquist, Susan, Khalil, Ahmad S.
Publicado no Cell (2017)

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

Por Tsvetkov, Peter, Mendillo, Marc L, Zhao, Jinghui, Carette, Jan E, Merrill, Parker H, Cikes, Domagoj, Varadarajan, Malini, van Diemen, Ferdy R, Penninger, Josef M, Goldberg, Alfred L, Brummelkamp, Thijn R, Santagata, Sandro, Lindquist, Susan
Publicado no eLife (2015)

The isolation and characterization of renal cancer initiating cells from human Wilms' tumour xenografts unveils new therapeutic targets†

Por Pode-Shakked, Naomi, Shukrun, Rachel, Mark-Danieli, Michal, Tsvetkov, Peter, Bahar, Sarit, Pri-Chen, Sara, Goldstein, Ronald S, Rom-Gross, Eithan, Mor, Yoram, Fridman, Edward, Meir, Karen, Simon, Amos, Magister, Marcus, Kaminski, Naftali, Goldmacher, Victor S, Harari-Steinberg, Orit, Dekel, Benjamin
Publicado em 2013