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A genetic tool to track protein aggregates and control prion inheritance

Protein aggregation is a hallmark of many diseases, but also underlies a wide range of positive cellular functions. These phenomena have been difficult to study due to a lack of quantitative and high-throughput cellular tools. Here we develop a synthetic genetic tool to sense and control protein agg...

詳細記述

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書誌詳細
出版年:Cell
主要な著者: Newby, Gregory A., Kiriakov, Szilvia, Hallacli, Erinc, Kayatekin, Can, Tsvetkov, Peter, Mancuso, Christopher P., Bonner, J. Maeve, Hesse, William R., Chakrabortee, Sohini, Manogaran, Anita L., Liebman, Susan W., Lindquist, Susan, Khalil, Ahmad S.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675731/
https://ncbi.nlm.nih.gov/pubmed/29056345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.041
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