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Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes

Prions are self-perpetuating aggregated proteins that are not limited to mammalian systems but also exist in lower eukaryotes including yeast. While much work has focused around chaperones involved in prion maintenance, including Hsp104, little is known about factors involved in the appearance of pr...

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Detalhes bibliográficos
Main Authors: Manogaran, Anita L., Hong, Joo Y., Hufana, Joan, Tyedmers, Jens, Lindquist, Susan, Liebman, Susan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098188/
https://ncbi.nlm.nih.gov/pubmed/21625618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001386
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