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Prion induction involves an ancient system for the sequestration of aggregated proteins and heritable changes in prion fragmentation
When the translation termination factor Sup35 adopts the prion state, [PSI(+)], the read-through of stop codons increases, uncovering hidden genetic variation and giving rise to new, often beneficial, phenotypes. Evidence suggests that prion induction involves a process of maturation, but this has n...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889312/ https://ncbi.nlm.nih.gov/pubmed/20421488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003895107 |
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