Loading...

Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation

Hsp100 and Hsp70 chaperones in bacteria, yeast, and plants cooperate to reactivate aggregated proteins. Disaggregation relies on Hsp70 function and on ATP-dependent threading of aggregated polypeptides through the pore of the Hsp100 AAA(+) hexamer. In yeast, both chaperones also promote propagation...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Winkler, Juliane, Tyedmers, Jens, Bukau, Bernd, Mogk, Axel
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413357/
https://ncbi.nlm.nih.gov/pubmed/22869599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201074
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!