A carregar...

Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation

Hsp100 and Hsp70 chaperones in bacteria, yeast, and plants cooperate to reactivate aggregated proteins. Disaggregation relies on Hsp70 function and on ATP-dependent threading of aggregated polypeptides through the pore of the Hsp100 AAA(+) hexamer. In yeast, both chaperones also promote propagation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Winkler, Juliane, Tyedmers, Jens, Bukau, Bernd, Mogk, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413357/
https://ncbi.nlm.nih.gov/pubmed/22869599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201074
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!