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Mechanism of regulation of Hsp70 chaperones by DnaJ cochaperones

Hsp70 chaperones assist a large variety of protein folding processes within the entire lifespan of proteins. Central to these activities is the regulation of Hsp70 by DnaJ cochaperones. DnaJ stimulates Hsp70 to hydrolyze ATP, a key step that closes its substrate-binding cavity and thus allows stable...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Laufen, Thomas, Mayer, Matthias P., Beisel, Christian, Klostermeier, Dagmar, Mogk, Axel, Reinstein, Jochen, Bukau, Bernd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21880/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10318904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.10.5452
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