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A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73
Protein degradation is an essential and highly regulated process. The proteasomal degradation of the tumor suppressors p53 and p73 is regulated by both polyubiquitination and by an ubiquitin-independent process. Here, we show that this ubiquitin-independent process is mediated by the 20S proteasomes...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546509/ https://ncbi.nlm.nih.gov/pubmed/15687255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.319905 |
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