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A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

Protein degradation is an essential and highly regulated process. The proteasomal degradation of the tumor suppressors p53 and p73 is regulated by both polyubiquitination and by an ubiquitin-independent process. Here, we show that this ubiquitin-independent process is mediated by the 20S proteasomes...

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Detalhes bibliográficos
Main Authors: Asher, Gad, Tsvetkov, Peter, Kahana, Chaim, Shaul, Yosef
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546509/
https://ncbi.nlm.nih.gov/pubmed/15687255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.319905
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