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Proteasome-independent p53 degradation

The intracellular levels of the p53 tumor suppressor protein are regulated through various pathways and involve numerous regulatory components. A recent study published in Cell Research identifies a proteasome-independent pathway of p53 protein degradation in the nucleolus that is dependent on Def a...

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Autori principali: Nuaaman, Mais M, Benchimol, Samuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641599/
https://ncbi.nlm.nih.gov/pubmed/23478295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.38
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