Def defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradation

p53 protein turnover through the ubiquitination pathway is a vital mechanism in the regulation of its transcriptional activity; however, little is known about p53 turnover through proteasome-independent pathway(s). The digestive organ expansion factor (Def) protein is essential for the development o...

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Detalhes bibliográficos
Main Authors: Tao, Ting, Shi, Hui, Guan, Yihong, Huang, Delai, Chen, Ye, Lane, David P, Chen, Jun, Peng, Jinrong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641591/
https://ncbi.nlm.nih.gov/pubmed/23357851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.16
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