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A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

Protein degradation is an essential and highly regulated process. The proteasomal degradation of the tumor suppressors p53 and p73 is regulated by both polyubiquitination and by an ubiquitin-independent process. Here, we show that this ubiquitin-independent process is mediated by the 20S proteasomes...

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Autores principales: Asher, Gad, Tsvetkov, Peter, Kahana, Chaim, Shaul, Yosef
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC546509/
https://ncbi.nlm.nih.gov/pubmed/15687255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.319905
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