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Oncogenic addiction to high 26S proteasome level

Proteasomes are large intracellular complexes responsible for the degradation of cellular proteins. The altered protein homeostasis of cancer cells results in increased dependency on proteasome function. The cellular proteasome composition comprises the 20S catalytic complex that is frequently cappe...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Tsvetkov, Peter, Adler, Julia, Myers, Nadav, Biran, Assaf, Reuven, Nina, Shaul, Yosef
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039477/
https://ncbi.nlm.nih.gov/pubmed/29991718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0806-4
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