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Oncogenic addiction to high 26S proteasome level
Proteasomes are large intracellular complexes responsible for the degradation of cellular proteins. The altered protein homeostasis of cancer cells results in increased dependency on proteasome function. The cellular proteasome composition comprises the 20S catalytic complex that is frequently cappe...
Gespeichert in:
| Veröffentlicht in: | Cell Death Dis |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6039477/ https://ncbi.nlm.nih.gov/pubmed/29991718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0806-4 |
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