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Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, γ-Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells

Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvements to current antioxidant therapeutic strategies a...

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Bibliografiske detaljer
Udgivet i:Antioxidants (Basel)
Main Authors: Hewson, Chris K., Capraro, Alexander, Wong, Sharon L., Pandzic, Elvis, Zhong, Ling, Fernando, Bentotage S. M., Awatade, Nikhil T., Hart-Smith, Gene, Whan, Renee M., Thomas, Shane R., Jaffe, Adam, Bridge, Wallace J., Waters, Shafagh A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760366/
https://ncbi.nlm.nih.gov/pubmed/33266084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121204
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