Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, γ-Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells

Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvements to current antioxidant therapeutic strategies a...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Hewson, Chris K., Capraro, Alexander, Wong, Sharon L., Pandzic, Elvis, Zhong, Ling, Fernando, Bentotage S. M., Awatade, Nikhil T., Hart-Smith, Gene, Whan, Renee M., Thomas, Shane R., Jaffe, Adam, Bridge, Wallace J., Waters, Shafagh A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760366/
https://ncbi.nlm.nih.gov/pubmed/33266084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121204
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