Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Por Awatade, Nikhil T., Wong, Sharon L., Hewson, Chris K., Fawcett, Laura K., Kicic, Anthony, Jaffe, Adam, Waters, Shafagh A.
Publicado no Front Pharmacol (2018)

Protein Traffic Disorders: an Effective High-Throughput Fluorescence Microscopy Pipeline for Drug Discovery

Por Botelho, Hugo M., Uliyakina, Inna, Awatade, Nikhil T., Proença, Maria C., Tischer, Christian, Sirianant, Lalida, Kunzelmann, Karl, Pepperkok, Rainer, Amaral, Margarida D.
Publicado no Sci Rep (2015)

Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis

Por Awatade, Nikhil T., Uliyakina, Inna, Farinha, Carlos M., Clarke, Luka A., Mendes, Karina, Solé, Amparo, Pastor, Juan, Ramos, Maria Margarida, Amaral, Margarida D.
Publicado no EBioMedicine (2014)

Partial rescue of F508del‐cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual‐acting smal...

Por Liu, Jia, Bihler, Hermann, Farinha, Carlos M, Awatade, Nikhil T, Romão, Ana M, Mercadante, Dayna, Cheng, Yi, Musisi, Isaac, Jantarajit, Walailak, Wang, Yiting, Cai, Zhiwei, Amaral, Margarida D, Mense, Martin, Sheppard, David N
Publicado no Br J Pharmacol (2018)