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Protein Traffic Disorders: an Effective High-Throughput Fluorescence Microscopy Pipeline for Drug Discovery

Plasma membrane proteins are essential molecules in the cell which mediate interactions with the exterior milieu, thus representing key drug targets for present pharma. Not surprisingly, protein traffic disorders include a large range of diseases sharing the common mechanism of failure in the respec...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Botelho, Hugo M., Uliyakina, Inna, Awatade, Nikhil T., Proença, Maria C., Tischer, Christian, Sirianant, Lalida, Kunzelmann, Karl, Pepperkok, Rainer, Amaral, Margarida D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356983/
https://ncbi.nlm.nih.gov/pubmed/25762484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09038
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