Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Cystic fibrosis (CF) is an inherited disorder where individual disease etiology and response to therapeutic intervention is impacted by CF transmembrane regulator (CFTR) mutations and other genetic modifiers. CFTR regulates multiple mechanisms in a diverse range of epithelial tissues. In this Review...

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Vydáno v:Front Pharmacol
Hlavní autoři: Awatade, Nikhil T., Wong, Sharon L., Hewson, Chris K., Fawcett, Laura K., Kicic, Anthony, Jaffe, Adam, Waters, Shafagh A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293199/
https://ncbi.nlm.nih.gov/pubmed/30581387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01429
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