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Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Cystic fibrosis (CF) is an inherited disorder where individual disease etiology and response to therapeutic intervention is impacted by CF transmembrane regulator (CFTR) mutations and other genetic modifiers. CFTR regulates multiple mechanisms in a diverse range of epithelial tissues. In this Review...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Awatade, Nikhil T., Wong, Sharon L., Hewson, Chris K., Fawcett, Laura K., Kicic, Anthony, Jaffe, Adam, Waters, Shafagh A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293199/
https://ncbi.nlm.nih.gov/pubmed/30581387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01429
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