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Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Cystic fibrosis (CF) is an inherited disorder where individual disease etiology and response to therapeutic intervention is impacted by CF transmembrane regulator (CFTR) mutations and other genetic modifiers. CFTR regulates multiple mechanisms in a diverse range of epithelial tissues. In this Review...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Awatade, Nikhil T., Wong, Sharon L., Hewson, Chris K., Fawcett, Laura K., Kicic, Anthony, Jaffe, Adam, Waters, Shafagh A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293199/
https://ncbi.nlm.nih.gov/pubmed/30581387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01429
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