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Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, γ-Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells

Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvements to current antioxidant therapeutic strategies a...

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Библиографические подробности
Опубликовано в: :Antioxidants (Basel)
Главные авторы: Hewson, Chris K., Capraro, Alexander, Wong, Sharon L., Pandzic, Elvis, Zhong, Ling, Fernando, Bentotage S. M., Awatade, Nikhil T., Hart-Smith, Gene, Whan, Renee M., Thomas, Shane R., Jaffe, Adam, Bridge, Wallace J., Waters, Shafagh A.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760366/
https://ncbi.nlm.nih.gov/pubmed/33266084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121204
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