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Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, γ-Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells

Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvements to current antioxidant therapeutic strategies a...

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Dades bibliogràfiques
Publicat a:Antioxidants (Basel)
Autors principals: Hewson, Chris K., Capraro, Alexander, Wong, Sharon L., Pandzic, Elvis, Zhong, Ling, Fernando, Bentotage S. M., Awatade, Nikhil T., Hart-Smith, Gene, Whan, Renee M., Thomas, Shane R., Jaffe, Adam, Bridge, Wallace J., Waters, Shafagh A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760366/
https://ncbi.nlm.nih.gov/pubmed/33266084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121204
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