The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ(40) Oligomers in Human Astrocytes

Glutathione (GSH) is one of the most abundant thiol antioxidants in cells. Many chronic and age-related diseases are associated with a decline in cellular GSH levels or impairment in the catalytic activity of the GSH biosynthetic enzyme glutamate cysteine ligase (GCL). γ-glutamylcysteine (GGC), a pr...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Braidy, Nady, Zarka, Martin, Jugder, Bat-Erdene, Welch, Jeffrey, Jayasena, Tharusha, Chan, Daniel K. Y., Sachdev, Perminder, Bridge, Wallace
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694290/
https://ncbi.nlm.nih.gov/pubmed/31440155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00177
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