The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ(40) Oligomers in Human Astrocytes

Glutathione (GSH) is one of the most abundant thiol antioxidants in cells. Many chronic and age-related diseases are associated with a decline in cellular GSH levels or impairment in the catalytic activity of the GSH biosynthetic enzyme glutamate cysteine ligase (GCL). γ-glutamylcysteine (GGC), a pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Aging Neurosci
Prif Awduron: Braidy, Nady, Zarka, Martin, Jugder, Bat-Erdene, Welch, Jeffrey, Jayasena, Tharusha, Chan, Daniel K. Y., Sachdev, Perminder, Bridge, Wallace
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694290/
https://ncbi.nlm.nih.gov/pubmed/31440155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00177
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