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Concurrent Hydrogenation of Three Functional Groups Enables Synthesis of C3´-Homologated Nucleoside Amino Acids
Internucleoside amide linkages are excellent mimics of phosphodiesters in RNA and may be used to optimize the properties of short interfering RNAs. Herein we report a remarkably straightforward, efficient and step economic synthesis of C3´-homologated uridine and adenosine amino acids starting from...
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| Gepubliceerd in: | Org Lett |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7755113/ https://ncbi.nlm.nih.gov/pubmed/28731724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01934 |
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