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Chemical approaches to discover the full potential of peptide nucleic acids in biomedical applications

Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a most dramatic departure from the native structure of DNA. The present review summarizes 30 years of research on PNA’s chemistry, optimization of structure and function, applications as probes and diagnostics, and...

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Dettagli Bibliografici
Pubblicato in:Beilstein J Org Chem
Autori principali: Brodyagin, Nikita, Katkevics, Martins, Kotikam, Venubabu, Ryan, Christopher A, Rozners, Eriks
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313981/
https://ncbi.nlm.nih.gov/pubmed/34367346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.116
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