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Chemical approaches to discover the full potential of peptide nucleic acids in biomedical applications

Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a most dramatic departure from the native structure of DNA. The present review summarizes 30 years of research on PNA’s chemistry, optimization of structure and function, applications as probes and diagnostics, and...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Brodyagin, Nikita, Katkevics, Martins, Kotikam, Venubabu, Ryan, Christopher A, Rozners, Eriks
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313981/
https://ncbi.nlm.nih.gov/pubmed/34367346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.116
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