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Impact of Chirality and Position of Lysine Conjugation in Triplex-Forming Peptide Nucleic Acids

[Image: see text] Conjugation with cationic lysine residues improves the biophysical and biological properties of peptide nucleic acids (PNAs). A single lysine is routinely used to improve the solubility and prevent aggregation of the neutral and hydrophobic amide backbone of PNA. Literature precede...

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Publicat a:ACS Omega
Autors principals: Ryan, Christopher A., Rozners, Eriks
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659144/
https://ncbi.nlm.nih.gov/pubmed/33195925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c04021
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