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Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs
RNA-based technologies to control gene expression, such as, RNA interference (RNAi) and CRISPR-Cas9 have become powerful tools in molecular biology and genomics. The exciting potential that RNAi and CRISPR-Cas9 may also become new therapeutic approaches has reinvigorated interest in chemically modif...
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| Udgivet i: | Acc Chem Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7751231/ https://ncbi.nlm.nih.gov/pubmed/32658452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.0c00249 |
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