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Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs

RNA-based technologies to control gene expression, such as, RNA interference (RNAi) and CRISPR-Cas9 have become powerful tools in molecular biology and genomics. The exciting potential that RNAi and CRISPR-Cas9 may also become new therapeutic approaches has reinvigorated interest in chemically modif...

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Bibliografiske detaljer
Udgivet i:Acc Chem Res
Main Authors: Kotikam, Venubabu, Rozners, Eriks
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751231/
https://ncbi.nlm.nih.gov/pubmed/32658452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.0c00249
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