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Monomers for preparation of amide linked RNA: Synthesis of C3’-homologated nucleoside amino acids from d-xylose

Amides as neutral and hydrophobic internucleoside linkages in RNA are highly interesting modifications for RNA interference. However, testing amides in siRNAs is hampered by the shortage of efficient methods to synthesize the monomeric building blocks, the nucleoside amino acid equivalents. This pap...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tanui, Paul, Kullberg, Martin, Song, Ni, Chivate, Yashodhan, Rozners, Eriks
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921610/
https://ncbi.nlm.nih.gov/pubmed/20725640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2010.04.110
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