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Monomers for preparation of amide linked RNA: Synthesis of C3’-homologated nucleoside amino acids from d-xylose
Amides as neutral and hydrophobic internucleoside linkages in RNA are highly interesting modifications for RNA interference. However, testing amides in siRNAs is hampered by the shortage of efficient methods to synthesize the monomeric building blocks, the nucleoside amino acid equivalents. This pap...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921610/ https://ncbi.nlm.nih.gov/pubmed/20725640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2010.04.110 |
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