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Synthesis and properties of triazole-linked RNA
RNA oligonucleotides having triazole linkages between uridine and adenosine nucleosides have been prepared and studied using spectroscopic techniques. UV melting and CD showed that triazole strongly destabilized RNA duplex (7 to 14 °C per modification). NMR data suggested that, despite relative flex...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099469/ https://ncbi.nlm.nih.gov/pubmed/21524577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.03.111 |
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