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Development and optimization of a high content analysis platform to identify suppressors of lamin B1 overexpression as a therapeutic strategy for Autosomal Dominant Leukodystrophy
Autosomal Dominant Leukodystrophy (ADLD) is a fatal, progressive adult-onset disease characterized by widespread central nervous system (CNS) demyelination and significant morbidity. The late age of onset together with the relatively slow disease progression provides a large therapeutic window for t...
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| Publicado en: | SLAS Discov |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7755098/ https://ncbi.nlm.nih.gov/pubmed/32349647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555220915821 |
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