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Development and optimization of a high content analysis platform to identify suppressors of lamin B1 overexpression as a therapeutic strategy for Autosomal Dominant Leukodystrophy

Autosomal Dominant Leukodystrophy (ADLD) is a fatal, progressive adult-onset disease characterized by widespread central nervous system (CNS) demyelination and significant morbidity. The late age of onset together with the relatively slow disease progression provides a large therapeutic window for t...

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Detaylı Bibliyografya
Yayımlandı:SLAS Discov
Asıl Yazarlar: Nmezi, Bruce, Vollmer, Laura L., Shun, Tong Ying, Gough, Albert, Rolyan, Harshvardhan, Liu, Fang, Jia, Yumeng, Padiath, Quasar S., Vogt, Andreas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755098/
https://ncbi.nlm.nih.gov/pubmed/32349647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555220915821
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