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Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4
BACKGROUND: The mechanism underlying the pain symptoms associated with chemotherapeutic-induced peripheral neuropathy (CIPN) is poorly understood. Transient receptor potential ankyrin 1 (TRPA1), TRP vanilloid 4 (TRPV4), TRPV1, and oxidative stress have been implicated in several rodent models of CIP...
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| Publicado no: | BMC Biol |
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| Principais autores: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7737339/ https://ncbi.nlm.nih.gov/pubmed/33317522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00935-9 |
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