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RB Regulates DNA Double Strand Break Repair Pathway Choice by Mediating CtIP Dependent End Resection
Inactivation of the retinoblastoma tumor suppressor gene (RB1) leads to genome instability, and can be detected in retinoblastoma and other cancers. One damaging effect is causing DNA double strand breaks (DSB), which, however, can be repaired by homologous recombination (HR), classical non-homologo...
Gorde:
| Argitaratua izan da: | Int J Mol Sci |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
MDPI
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7730402/ https://ncbi.nlm.nih.gov/pubmed/33271982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239176 |
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