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RB Regulates DNA Double Strand Break Repair Pathway Choice by Mediating CtIP Dependent End Resection
Inactivation of the retinoblastoma tumor suppressor gene (RB1) leads to genome instability, and can be detected in retinoblastoma and other cancers. One damaging effect is causing DNA double strand breaks (DSB), which, however, can be repaired by homologous recombination (HR), classical non-homologo...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7730402/ https://ncbi.nlm.nih.gov/pubmed/33271982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239176 |
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