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Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules

[Image: see text] Protein–protein interactions (PPIs) are involved in many of life’s essential biological functions yet are also an underlying cause of several human diseases, including amyloidosis. The modulation of PPIs presents opportunities to gain mechanistic insights into amyloid assembly, par...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Cawood, Emma E., Guthertz, Nicolas, Ebo, Jessica S., Karamanos, Theodoros K., Radford, Sheena E., Wilson, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729939/
https://ncbi.nlm.nih.gov/pubmed/33253560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c10629
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