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Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules

[Image: see text] Protein–protein interactions (PPIs) are involved in many of life’s essential biological functions yet are also an underlying cause of several human diseases, including amyloidosis. The modulation of PPIs presents opportunities to gain mechanistic insights into amyloid assembly, par...

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Publicat a:J Am Chem Soc
Autors principals: Cawood, Emma E., Guthertz, Nicolas, Ebo, Jessica S., Karamanos, Theodoros K., Radford, Sheena E., Wilson, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729939/
https://ncbi.nlm.nih.gov/pubmed/33253560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c10629
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