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Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules

[Image: see text] Protein–protein interactions (PPIs) are involved in many of life’s essential biological functions yet are also an underlying cause of several human diseases, including amyloidosis. The modulation of PPIs presents opportunities to gain mechanistic insights into amyloid assembly, par...

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Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Cawood, Emma E., Guthertz, Nicolas, Ebo, Jessica S., Karamanos, Theodoros K., Radford, Sheena E., Wilson, Andrew J.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729939/
https://ncbi.nlm.nih.gov/pubmed/33253560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c10629
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