LPAR2 receptor Activation Attenuates Radiation-Induced Disruption of Apical Junctional Complexes and Mucosal Barrier Dysfunction in Mouse Colon

The tight junction (TJ) and barrier function of colonic epithelium is highly sensitive to ionizing radiation. We evaluated the effect of lysophosphatidic acid (LPA) and its analog, Radioprotein-1, on γ-radiation-induced colonic epithelial barrier dysfunction using Caco-2 and m-IC(C12) cell monolayer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Shukla, Pradeep K., Meena, Avtar S., Gangwar, Ruchika, Szabo, Erzsebet, Balogh, Andrea, Lee, Sue Chin, Vandewalle, Alain, Tigyi, Gabor, Rao, RadhaKrishna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725959/
https://ncbi.nlm.nih.gov/pubmed/32654268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000544R
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg