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Phosphorylation hotspot in the C-terminal domain of occludin regulates the dynamics of epithelial junctional complexes

The apical junctional complex (AJC), which includes tight junctions (TJs) and adherens junctions (AJs), determines the epithelial polarity, cell-cell adhesion and permeability barrier. An intriguing characteristic of a TJ is the dynamic nature of its multiprotein complex. Occludin is the most mobile...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Manda, Bhargavi, Mir, Hina, Gangwar, Ruchika, Meena, Avtar S., Amin, Shrunali, Shukla, Pradeep K., Dalal, Kesha, Suzuki, Takuya, Rao, RadhaKrishna
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963837/
https://ncbi.nlm.nih.gov/pubmed/29507118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.206789
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