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Rapid disruption of intestinal epithelial tight junction and barrier dysfunction by ionizing radiation in mouse colon in vivo: protection by N-acetyl-l-cysteine

The goals of this study were to evaluate the effects of ionizing radiation on apical junctions in colonic epithelium and mucosal barrier function in mice in vivo. Adult mice were subjected to total body irradiation (4 Gy) with or without N-acetyl-l-cysteine (NAC) feeding for 5 days before irradiatio...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Gastrointest Liver Physiol
Hoofdauteurs: Shukla, Pradeep K., Gangwar, Ruchika, Manda, Bhargavi, Meena, Avtar S., Yadav, Nikki, Szabo, Erzsebet, Balogh, Andrea, Lee, Sue Chin, Tigyi, Gabor, Rao, RadhaKrishna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867328/
https://ncbi.nlm.nih.gov/pubmed/26822914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00314.2015
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