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Rapid disruption of intestinal epithelial tight junction and barrier dysfunction by ionizing radiation in mouse colon in vivo: protection by N-acetyl-l-cysteine
The goals of this study were to evaluate the effects of ionizing radiation on apical junctions in colonic epithelium and mucosal barrier function in mice in vivo. Adult mice were subjected to total body irradiation (4 Gy) with or without N-acetyl-l-cysteine (NAC) feeding for 5 days before irradiatio...
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Gepubliceerd in: | Am J Physiol Gastrointest Liver Physiol |
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Hoofdauteurs: | , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
American Physiological Society
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867328/ https://ncbi.nlm.nih.gov/pubmed/26822914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00314.2015 |
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